III. Chicago Keloid Treatment:
There is no satisfactory keloid treatment.
Some doctors have had success injecting keloids with Kenalog or Bleomycin, an anticancer drug.
The most accepted keloid treatment is to inject a long-acting cortisone into the keloid once a month. After several injections with cortisone, the keloid usually becomes less noticeable and flattens in three to six months time.
A new keloid treatment is to apply a silicone gel preparation over the keloid scar for 12-24 hours each day. This treatment is started three to four weeks after the wound or injury. The gel preparation should be covered with an ace bandage, cloth wrap, or tape and changed every 7-10 days based upon need. The gel can be washed and used over each day. An even newer form of silicone that is more convenient is Scar Guard (applied like nail polish and contains cortisone, Vitamin E and silicone). With daily use, the keloid will become flatter and smoother within two to twelve months.
Surgery is always an option but one must remember – the keloid can always come back – sometimes even bigger! Most patients need to be watched after surgery to assess the need for cortisone shots if it looks like the keloid is coming back. That is why follow-up appointments are very important. More aggressive treatment includes radiation therapy after surgery to decrease recurrence rates.
Very recently, pre-treatment with Retin-A cream 3 weeks prior to surgical removal has been noted to dramatically reduce the incidence of recurrence.